Interior architectural styles are reflected in door frames remodeled to incorporate Greek Revival on one side, leaving the original Federal style intact on the other side. The two styles are cleverly merged through a change in the shape of the balusters at an upper landing. Lighting fixtures, originally candle and oil lamps, were replaced by gas sconces and later, by electric lamps. Other manifestations of "contemporary" remodeling abound.

The Nichols House Museum is open to the public as an historic house museum reflecting the domestic life of a typical family of Beacon Hill at the turn of the last century. The museum is part of the historical legacy of one of the most famous neighborhoods of America. Located at the heart of Beacon Hill, the Nichols House Museum receives visitors from many foreign countries and from all over the United States.